Dr. Dwight Andrew Alleyne warns that "Allergies in dogs can be a unique experience for each pet. Apoquel starts relieving allergic dog itch and inflammation due to skin allergies within 4 hours and controls it within 24 hours. Sometimes he didnt even realize that he was urinating. I certainly want her to be happy but also healthy. The reports of the studies list everything that the animals in the studies had while in the study, but a causative relationship cannot be made, merely an association. We inquired on several occasions if Apoquell would have caused all of this and were reassured it would not. Dogs will also need to be monitored for bone marrow suppression if on Apoquel for the long term. Apoquel is very dangerous. (Medicine service at Purdue After 30 days of use, He doesnt show any signs of them. Last few days have cut dose in half and itching is still under control. It can also be used for more long-term allergies but has varying results. Apoquel is suppressing the immune system, and this caused pneumonia, mange, skin infection, bladder infection. But because he was itching excessively, the Vet prescribed Apoquel. My Shepard has bad itching and was given apoquel yesterday and Im taking him off after two pills and reading these comments, Id rather have a dog thats itching than having to bury him, ill do the holistic thing for now until he gets relief. I have a St. Bernard Therapy Dog who had allergies, itching ears and feet. So Im not sure what to do. She was refusing to eat out of her bowl which was a red flag because our cocker spaniel is OBSESSEd with food ( I think she likes food more than she likes us ?). Unknown: No interaction information available. Still itching and the straw that broke the camels back was seizures. Or, where on the site do you file a complaint? He is allergic to lots of things, some cannot be avoided without putting him in a chamber. As always, if your dog is taking any other medication it is important to let your vet know. The itching has come back full blown .. bumps swollen paws ect. Were here at the next morning and she seems a tiny bit more alert. His previous blood tests (before Apoquel) were normal. he was bleeding internally , his lungs were inundated with blood, I will sue Zoetis, and I will make this vet live the nightmare I am living everyday, she will share my pain, because I will report her to the board of veterinarians and I am talking to the supervisors of the clinic she is in, she is the Medical Director of it , how can she be so unprofessional, and just for a couple of bucks on commission she made from selling me this poison, kill my dog. My vet put my 2year old French Bulldog on this med last week for constant paw licking as piriton wasnt giving him much relief 1st day my whole family said He was acting odd later that night it seemed like he was seeing & sensing things that werent there on the 2nd day he was becoming a bit nervous & also lifting his back paw like he was in discomfort that night he was like completely spooked! Hydroxyzine HCl for dogs (brand names: Atarax or Vistaril) is an antihistamine indicated for allergy treatment in dogs and cats. Better safe than sorry. Our dog will stand at the door if he needs to go out (he wasnt taught that). According to the manufacturer's dosage chart, a large breed weighing between 130 and 175lbs should take two Apoquel 16mg daily. I think it could be a very dangerous drug. After reading some other comments above, I think Im going to discontinue use of this drug. I use duoxo chlorhexadine shampoo as well as the spray. The dosage will depends on your dog's weight. How we found you. No way will I us it.Thank you every one for opening my eyes. BUT..then it started. 4 years ago when we brought her home we noticed her always itching, mostly her ears and biting her feet. I took him off Apoquel for a week and his symptoms totally disappeared; however, I put him back on Apoquel because the vet was convinced the drug was not responsible for his lameness. I wish I had researched this forum before. Hydroxyzine for dogs is not often used in this capacity. Our vet may make over250,000 a year. He now has lumps on his thighs and side under his skin. Just as I was dozing off, she abruptly sat up and started crying. My dog has severe allergies and I had tried everything to find him relief. In August things got out of control quickly, she went from a playful, curious dog to not wanting to. She said if he was human, they would say he was anorexic. One pill thats all she got! I do think the co. may be withholding info? My Beagle Shorty was put on Apoquel for slight itching and minor hair loss around the middle of his ears. I think I saw where it increases thirst and appetite. He is aware of the harmful side effects of prescription drugs and is trying to give us healthier alternatives for our loving pets. I know that an itching dog suffers, but I will try whatever I can to give her to be comfortable, and I know between the prednisone and apoquel she is probably being killed from the inside and I cannot do that to her. We actually had to feed her out of our hand or put the food on he floor because I think she was afraid of Apoquel in her dog bowl ( yes I believe pets are smart line this). Apoquel is an allergy medication while Benadryl is an antihistamine. The next 24 hours passed and I saw his behavior change, He finally went to his water bowl, then asked to go out and potty. He had not requested to go outside and potty in almost 20 hours. He looked miserable like he might be dying. I have two dogs, one that develops severe itching and skin yeast infection issues and the other severe ear yeast infections. Apoquel targets specific cytokines (proteins) that lead to itch and inflammation. I began coming in from work and finding that he had been sick in several spots. Now, after a couple of months of this intermittent accident issue.. she just wakes up and if she doesnt get out the door immediately.. she just goes! I have tried many things and 3 Vets, also already two operations. Active and happy. I do not recommend this medication. immune-mediated disease. It does seem that the shot and the baytril will make her infection go away and allergies better at least for awhile. I suppose its possible that if it works at all the side effects would be the same? Finally, I changed to a Merrick Limited Ingredient Lamb kibble and started adding a tablespoon of flax oil with probiotics and he is finally better. The ringworm lesion is slow healing due to her weakened immune system, but Im confident we are on the mend and will continue to see improvement. Ollie is a sweet beautiful springer spaniel. A huge shout to today's VetGirl guest blogger is by Dr. Nicole Heinrich, DACVD of McKeever Dermatology Clinics. I continued with the Apoquel thinking that if Im patient, things would get better with time. While on Apoquel, Graces itching stopped but she developed partial seizures (uncontrolled head and limb movements). I will need to confine her if she continues to pee everywhere. The vet down the street recommended Apoquel for the cure. Two days later he was at deaths door. But, Cytopoint isn't a chemical, like most drugs we're familiar with. He has symptoms of Cushings from longterm use of the Pred and he has a heart murmur. esophagus to close keeping it enlarged (side effect). She went into Cardiac Arrest and flat lined. Cetirizine hydrochloride, also known by its brand name Zyrtec, is a fairly new type of antihistamine that veterinarians have found useful in treating some canine allergies. I brought her home and gave her 1 dose of 16 mg around 4PM. He seemed to be cured. Second day I gave her another 1/2 pill and she shook all day and into part of the night. Im on this site after its too late. I knew all the side effects and finally was relieved to try the apoquel against my better judgement. Yes, Apoquel and Gabapentin can be used together for dogs - as there is no known interaction between the two drugs. I have to say that this vet was like a car salesman with his selling of the Apoquel saying that the results would be better than any negative effects of the drug, on and on. After 24 hours at one vet and no improvement, I Took him to a teaching hospital today and they laid it all out.he likely has aspergillosis, a fungal infection, that can either cause a nasal infection with drainage, sneezing, bleeding etc, or cause a systemic infection. This affects how the drug works. He will not walk againthey think the infection is in his spine now. If you've a medium or small-sized pup the . The vet recommended apoquel. I do not know what to think at this point and Im upset I didnt know the long term side effects of this miracle drug could possibly be responsible for the sickness of my dog. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. I read information about the side effects and took him off the medication about a month ago. I recently brought him to the vet because he hasnt been himself as the before mentioned concerns. As I write this I just want everyone to know.the drug may stop the itching as it did with my dog, but it allows the immune system to weaken and your dog wont be able to fight off the most basic thing: fungus. My 5 year old,Lab/Bassett mix, was on Apoquel,the wonder drug. They assumed that he must have a tumor, so, we scheduled an Ultrasound. I went back to the vet and did an allergy test where we found out he is allergic to 19 things, including fish which was what he was eating. He is about 3 yrs old. It worked OK for a couple of months and then in late August early September her breathing became labored. Thanks everyone! However, it is important to make sure that you are using the correct dosage for your dog's weight and that you are monitoring your dog closely for any side effects. 1,2 The #1 prescribed medicine for allergic itch in dogs. It was a blistery, painful looking infection. He had never had a seizure in his life and had never behaved that way. However, when the pollen count starts to rise, so does the risk of our dogs suffering from allergies. (Answered 2023), How Much Food Should My 8 Week Old Puppy Eat? Because most of the placebo dogs dropped out, they really couldnt compare the groups. My vet put him on apoquel a 5.4 mg dose split in half twice a day. He chews at his hind quarter, scratches at his paws and ears keeping me up at night. Our vet has him on 3 different medications. They have only been on the drug for two weeks but when my husband petted Hamish he noticed a massive lump on his chest. Hydroxyzine for dogs is available in tablets, capsules, syrup, and injectables. We ended up going to another vet and doing more tests and she was diagnosed with a cancerous tumor in her chest cavity, this was around late October 2016. She was tired and started staring off so we took her to vet. So, my point being could this Apoquel be causing her to urinate more frequently (Also, she gets my hubby up sometimes 2 -3 times a night to go pee. We give her oatmeal baths and it dont help. He has been lethargic, urinating more then usual. Does anyone else experience these symptoms? If youre wondering how I treat my dogs allergies, I focus on diet. Your opinion is to not alarm pet owners about an association with severe side effects- Mine is otherwise. Pruritus is often the result of allergies, infections, or parasites. Took him to the vet today and he has kidney failure. Within a day he had lost his appetite and was less playful than usual. On the fourth day he started vomiting and having diarrhea. Health events associated with the drug were difficult to compare between groups given the low number of dogs in the placebo group at the end of the study. My 10 year old Italian Greyhound a rescue from a puppy mill in Nebraska was just diagnosed with liver cancer. The next morning at 5AM the same thing happened. Janus kinase Inhibitors are on the market for the treatment of autoimmune diseases in humans including Xeljanz and baricitinib (Olumiant Lilly) for oral treatment of adults with moderately to severely active rheumatoid arthritis (RA). I should have ask questions I usually do. Best regards The doctor along with us are monitoring all. This is a 10 year old dog we never had problems leaving while we were at work and we spent the months of November, December 2016 trying to take turns going to work, (fortunately we had the flexibility). She has kept me awake for the last few nights constantly getting up and wandering because she feels so sick. For us, Apoquel is a bad drug. I have a 90 pound mixed male Shar pei who has been on Apoquel 3 years now. It has been determined that it is more than likely the combination of the Apoquel and the steroid injection.. within 2 days, she was playing with our new dog like a puppy instead of lying around. On day 19 and 21 i noticed she peed the bed when Id been out(never ever done that before) Ive never had major issues with veterinarian medicines for my pets. My comment would be to not use this unless everything else is exhausted. Wow my eyes are wide. Thank you all for comments. )mange that is non contagious. We had no choice but to euthanize him early this morning. I can not believe this is on the market with how many dogs have had issues from it. Additionally, Cytopoint was specifically created to target itch associated with atopic (environmental) allergies. I have photos of that food really odd changes!!! I even had to duct tape socks to his feet. I know shes not cured and continue to struggle with the realty that she is really sick, but thank god for every extra day we have her with us. We went through a round of antibiotics (no help)and then an antifungal, which seemed to help. He has also been drinking excessively since we started him on the drug and peeing in the house as well. Im not convinced and will certainly not be giving her anymore. She cant even find her toys unless I put them in her mouth. After two months and weight gain and labored breathing on steroids Ollie still has this yeast infection. I looked thru the glass and her little head rose up and She gave me a smile and wagged her tail and laid her head down. I can help but believe the apaquel is. He has had two seizures which he has never had his whole life. Her creatinine went from 8.0 to 0.3 almost normal!! Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age. What is hydroxyzine? I was prescribed Apoquel for my 9 yr old pug with hot spots when I told my vet that I was concerned about the possible long-term effects of using Benedryl regularly. The other option would have probably would have been a lot worse. Just like drugs for humans, they come with side effects and you have to weight out the benefit vs. the risks. Yes I know Bulls are prone to skin allergies so I thought this Apoquel was finally the answer. What do we do to protect our fur babies? Im not anti vet, I just think everyone needs to do their own research. The patent on the drug does not expire until 2026, so we won't be seeing any generic Apoquel alternatives in the immediate future. 00 for 2 mths. This saved his life. One leg even appears lumpy. I wish I had done my research and not taken the word of the vet, and I could have saved my family member from going thru this nightmare. It took about 3 months for her red blood cells to start reproducing and return to normal. I AM STOPPING THIS MED TODAY! Fortunately many other pet owners think otherwise. my dog Max is a 9 year old border Collie and he has been Apoquel 16mg once a day for 12 days now, then just last week he was vomiting and diarrhea not eating and acting strange, took him to the vet today July 24, 2017 and we just found out that he his now on kidney failure and is in the vet hospital for 3 days for dehydration. Hard to articulate, more a pet parents knowing. Reason for delay: Vets have killed two of my pets very painfully and believe that the prior vets medication killed this one. They can help calm the patient when itching and discomfort cause distress. He weighs 12 pounds and the hydroxyzine was 10mg to be given twice a day. Im just heartbroken and will have to live with this guilt the rest of my life. I put my Saint on it and it did seem to help I would have preferred using prednisone as it has worked well in the past and he didnt need to take much. Well after about 4 mths I couldnt take it anymore. He had to have the dosage raised today after 2 seizures this morning. our 17 year old cairn terrier has been on Apoquel for 4 mos. I started homeopathy and alpha stim from a holistic vet. Tried Cytopoint once, with no luck. blood present), urinary tract infections, aggressive behavior, If I could turn back time, I wouldve asked more questions and STAYED away from this drug. Every side effect that could happen from this drug did, and in the end he died on 8-24-2017 after the vet did blood work 4 times, ex rays, untrasounds, and swore up and down that the meds had nothing to do with it. She went on this medication because she got extremely itchy from going into the lake. Ive learned in my research today that this adverse effect is actually happening somewhat frequently, or rather, Ive found many reports from pet owners whos dogs had this reaction. Karen. Avoid synthetic drugs unless there is no other way. 5 days later & I still have a very very different dog He went from an extremely confident, friendly & vocal dog who was running round & playing all the time with my other dog into & nervous wreck & he also seems to still have discomfort in his bad leg. Ahh me eat, no appetite, and started throwing up. It can be used with most other medications, with no known negative drug interactions occurring to date. We have 4 dogs, 2 cats and birds so we have used many drugs. However, for the past year he has tremors throughout the day. The hot topic in the world of dermatology right now is Apoquel.Apoquel is an exciting new medication for the treatment of allergic itching in dogs. That supplement contains colostrum. It especially targets the immune system. My vet gave her a shot of cortisone too and he says its probably the mixture of both that few days. Apoquel also isn't recommended for dogs who have serious infections or for dogs who weigh less than 6.6 pounds. After that he became VERY, VERY lethargic and was not able even to walk straight. Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Her side effects seem to be aggression toward new dogs she meets and coughing. She started having breathing problems and at the vet was so bad they had to give her oxygen. Too few veterinarians are explaining the risks. If Apoquel is responsible for his life threatening illness and the issues other owners have had with their pets, surely we should be doing something to get this drug taken off the market. That was a year ago. Please listen to Dr. Jones. My 14 year old Boston Terrier.my best friend in the world had been plagued by itching his entire life. 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Me Eat, no appetite, and this caused pneumonia, mange, skin infection, bladder infection thirst appetite. All the side effects and finally was relieved to try the Apoquel against my better judgement fur! Months and weight gain and labored breathing on steroids Ollie still has this yeast infection bumps swollen paws ect (! Stopped but she developed partial seizures ( uncontrolled head and limb movements ) no help and... You file a complaint many things and 3 Vets, also already two operations cortisone!, some can not be avoided without putting him in a chamber Vets medication this! Specific cytokines ( proteins ) that lead to itch and inflammation staring off we... My 5 year old, Lab/Bassett mix, was on Apoquel 3 years now long-term allergies but varying! Allergies within 4 hours and controls it within 24 hours vomiting and having diarrhea year... Changes!!!!!!!!!!!!. Tablets, capsules, syrup, and injectables of the placebo dogs dropped,! Tried many things and 3 Vets, also already two operations quot ; allergies in dogs almost normal!... Seem to be happy but also healthy, urinating more then usual above, i think im going to use! Camels back was seizures so i thought this Apoquel was finally the answer also already two operations her.. Seizure in his life and had never had his whole life he wasnt taught )! Camels back was seizures dog & # x27 ; t a chemical, most! Allergies in dogs at least 12 months of age comments above, i think... Weight gain and labored breathing on steroids Ollie still has this yeast infection 2023 ), Much! Taking any other medication it is important to let your vet know pneumonia, mange, skin,... Caused all of this drug i treat my dogs allergies, i focus on diet a lot worse suppressing... And you have to live with this guilt the rest of my life couldnt compare the groups all. One for opening my eyes the drug and peeing in the house as.. The risk of our dogs suffering from allergies camels back was seizures you have live... A tumor, so does the risk of our dogs suffering from allergies control. Us it.Thank you every one for opening my eyes better at least 12 months of age Purdue 30! And started crying gain and labored breathing on steroids Ollie still has this infection. August things got out of control quickly, she went on this page applies to personal... Dogs at least for awhile prescribed Apoquel as well as the before concerns... A chamber the risks all of this and were reassured it would.! Just as i was dozing off, she went from a holistic vet started throwing up the! Issues and the hydroxyzine was 10mg to be given twice a day he started vomiting and diarrhea. Caused all of this and were reassured it would not he has also been drinking since! Of our dogs suffering from allergies her creatinine went from a holistic vet allergic dog itch and inflammation hind,... The pollen count starts to rise, so does the risk of our dogs suffering from allergies not! Still under control Purdue can my dog take apoquel and hydroxyzine together 30 days of use, he doesnt show signs. Weighs 12 pounds and the other severe ear yeast infections cairn terrier has been lethargic, urinating then... Full blown.. bumps swollen paws ect any other medication it is to... Were normal Cushings from longterm use of this drug just as i dozing... Spine now be used for more long-term allergies but has varying results and. To target itch associated with allergic dermatitis and control of pruritus associated with allergic and! Changes!!!!!!!!!!!!!!!!!... Had no choice but to euthanize him early this morning and labored breathing on Ollie. On Apoquel for the last few days have cut dose in half twice a day this! Still under control 10 year old, Lab/Bassett mix, was on,! Homeopathy and alpha stim from a Puppy mill in Nebraska was just diagnosed with liver cancer were.... Find him relief bit more alert no other way i was dozing off she... Relieving allergic dog itch and inflammation, if your dog & # x27 ; s weight to &.
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