When this happens, more cholesterol can then be cleared from your blood by your liver. It also isnt known how many adults and children experienced joint pain in clinical studies of Zetia used to treat other conditions. You should always consult your doctor or another healthcare professional before taking any medication. Ways to reduce the symptoms. (Mixed hyperlipidemia is also known as mixed high cholesterol.). Most of these side effects may go away within a few days or a couple of weeks. zetia. Talk with your doctor about birth control options that may be best for you. In the studies, total cholesterol levels: To learn how Zetia and the placebo affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. For this purpose, Zetia is used with a low-cholesterol diet and is taken with atorvastatin or simvastatin in adults and in children ages 10 years and older. Researchers analyzed data on nearly 300,000 patients from the Cedars-Sinai Health . 2005-2023 Healthline Media a Red Ventures Company. Use of the terms male and female in this article refers to sex assigned at birth. To learn how Zetia and the other treatments in the study affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. People who may be at higher risk of this side effect include those who: Tell your doctor if any of the above apply to you before starting Zetia treatment. 2. Examples of mild side effects that have been reported with Zetia include: * To learn more about this side effect, see the Side effects explained section below. Examples of statin drugs include atorvastatin (Lipitor) and simvastatin (Zocor). If you develop serious side effects while taking Zetia, call your doctor right away. It belongs to a class of drugs called cholesterol absorption inhibitors. Zetia side effects. The side effects from Zetia .. muscle weakness, joint pain, upper respiratory infectikns resemble the symptoms of malabsorption of Vitamin A,D, E and K. Our bodies need cholestorol to help coat our nerves and help with brain function and it naturally increases as we get older, so why are we trying to lower it, could this be why we are . Zetia may also be used off-label for other conditions. Fenofibrate is a drug used to lower your triglyceride levels. Zetia contains the active drug ezetimibe. Recently, POTS has been diagnosed in some people who have had COVID-19. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. Before starting a new medication, its a good idea to talk with a healthcare professional about any questions or concerns you may have. Postural orthostatic tachycardia syndrome (POTS) is a condition that causes a number of symptoms when you transition from lying down to standing up, such as a fast heart rate, dizziness and fatigue. For most people, CoQ10 isnt a harmful or dangerous supplement. Crestor is part of the statin drug class. No, stopping Zetia shouldnt cause any side effects. Pots or postural tachycardia syndrome is, also known as postural orthostatic tachycardia syndrome, is a condition that affects the flow of blood in the heart and brain. voice changes. For more information, see the How Zetia works section below. What is considered high cholesterol? In clinical studies that lasted an average of 12 weeks, Zetia was compared with a placebo (a treatment with no active drug). Over an average of 8 to 12 weeks, people took either Zetia alone, Zetia with a statin drug, a statin drug alone, or a placebo. Zetia is FDA-approved to treat certain types of high cholesterol in adults and in children when used with a low-cholesterol diet. As with all medications, the cost of Zetia can vary. (Primary hyperlipidemia is also called primary high cholesterol.) Get emergency medical help if you have signs of an allergic reaction to Zetia: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Taking Zetia with cyclosporine (a drug that suppresses your immune system) can raise the levels of both medications in your body. * To learn more about this side effect, see the Side effects explained section below. Zetia can interact with several other medications. We've provided a list of the best at-home tests for. Before taking Zetia, talk with your doctor and pharmacist. This makes it difficult to keep an upright posture without abnormal heart-rate (tachycardia) and/or sympathetic activity. Across studies, researchers looked at different groups of people to evaluate whether Zetia was safe and worked for their condition. If you think youve taken too much of this drug, call your doctor. Call your doctor right away if you have serious side effects. Learn about the drugs dosages, forms, strengths, and more. No, hair loss isnt a known side effect of Zetia. Lipitor contains the active drug atorvastatin. Here are answers to some frequently asked questions about Zetia. Primary hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. POTS is a form of "autonomic dysregulation" (a nervous system disorder) in which your heart rate spikes upon standing (among other symptoms). You should always consult your doctor or another healthcare professional before taking any medication. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. Dont take an extra dose to make up for your missed dose. Ezetimibe (the active drug in Zetia) is also available in a combination drug that contains simvastatin. Here are some natural statins that may help keep your cholesterol in a healthy. Medications in the fibrate drug class may increase the amount of cholesterol thats stored in your gallbladder. (A class of drugs is a group of medications that work in a similar way.) These lists dont include all possible side effects. Clinical studies have shown Zetia to be effective for treating homozygous familial hypercholesterolemia when used with atorvastatin or simvastatin. You should take Zetia according to the instructions of your doctor or another healthcare professional. Clinical studies have shown Zetia to be effective for treating primary high cholesterol when used alone or with statin drugs. If youd like to notify the FDA about a side effect youve had with Zetia, visit MedWatch. Zetia may be used with statin drugs to treat the following conditions in adults: Statins are another class of medications used to lower cholesterol. * Sex and gender exist on spectrums. Its a place where people with certain conditions can find support and connect with others. 1. Zetia may be used with statin drugs or with fenofibrate when used to treat certain conditions. Zetia does not cause an increase or a decrease in blood pressure. Hot and cold spells. Learn more about how grapefruit may interact with medications. * Zetia is also approved to treat these conditions in children ages 10 years and older. A clinical study looked at children ages 10 to 17 years old with heterozygous familial hypercholesterolemia (HeFH). Its also unknown how many adults and children experienced muscle weakness or muscle breakdown in these studies. Theyll likely suggest changes to your treatment plan. Zinnia elegans 'Benary's Giant Golden Yellow'. They can recommend treatments that may help with joint pain, or they may recommend a different treatment option for you. If you have kidney problems, you may experience even higher levels of Zetia in your body. Statins lower cholesterol by preventing your liver from making new cholesterol. If any of the following factors or conditions apply, you may have a higher risk of developing these muscle problems: If you have muscle-related side effects during Zetia treatment, talk with your doctor. If youre breastfeeding or planning to breastfeed while taking Zetia, talk with your doctor about the risks and benefits. 5.8k views Answered >2 years ago. You can learn more about how we ensure our content is accurate and current by reading our. However, animal studies dont always predict what will happen in humans. Memory loss isnt a side effect of Zetia. Zetia is a lipid-lowering compound used to treat high cholesterol.Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint pain, muscle aches, and sinus infection ().. Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash . Brain fog. In people with POTS, more blood collects in the lower body when standing upright. Its not known if Zetia is safe to take during pregnancy. If you already have liver problems, taking Zetia may worsen your condition. Zetia contains the active drug ezetimibe. It can be taken with or without fenofibrate in adults. Porphyrias have been associated with POTS symptoms (Stewart & Hensley, 1981). However, several medicines can be prescribed off-label when needed. Tell your doctor right away if you become pregnant while taking Zetia with a statin drug. (For more information, see Liver problems in the Warnings for Zetia section above.). If youre taking a statin drug with Zetia, they may recommend that you take a supplement called coenzyme Q10 (CoQ10). However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. These include symptoms such as muscle pain, muscle weakness, and muscle cramps. Read More. These drugs havent been directly compared in clinical studies. Phil Fischer, M.D., medical director of Mayo Clinic's children's hospital and a POTS specialist, led . The phase IV clinical study analyzes which people take Zetia and have Constipation. . (A class of medications is a group of drugs that work in a similar way.) Zetia is available in a generic form called ezetimibe. For more information, see the prescribing information for Zetia and Crestor. Dizziness is a rare side effect of taking Zetia. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. Other side effects not listed may also occur in some patients. If you feel dizzy from Zetia, it may help to take your dose at bedtime. Its FDA-approved to treat certain forms of high cholesterol in adults and in children ages 10 years and older. Your doctor may prescribe Zetia with a statin drug. Do my other medications increase my risk of side effects with Zetia? Mild side effects of Zetia when taken with a statin (another kind of cholesterol -lowering drug) may include: infection, such as a respiratory . This can increase your risk of side effects from either medication. Most women describe brain zaps, also known as brain shivers or head shocks, as a repetitive electric-like sensation in the head. Crossing your legs in front of each other while standing, rocking up and down on your toes. Ezetimibe may cause side effects. Your doctor may do liver function tests before you start treatment and regularly during your Zetia treatment. Zetia may cause joint pain. Your doctor or pharmacist can help you choose one that doesnt have extra ingredients that you dont need. Zetia (ezetimibe), a drug that reduces the amount of dietary cholesterol absorbed from the small intestines, is not associated with either weight gain or weight loss. You may be more likely to develop this side effect if you take Zetia with a statin drug. For more information about Zetia, including details about its uses, see this in-depth article on the drug. These problems can include muscle pain and muscle weakness, and rarely, muscle breakdown. In the studies: Zetia is approved to treat the following conditions in children ages 10 years and older when used with a low-cholesterol diet: To learn more about how Zetia is used for these conditions, see the sections above. However, excessive alcohol use can damage your liver over time. Stomach pains were gone after second day. Specific statins that were studied included atorvastatin (Lipitor), simvastatin (Zocor), pravastatin (Pravachol), and lovastatin. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. For HoFH, Zetia is FDA-approved to decrease levels of total cholesterol and LDL cholesterol. Talk with your doctor if youre concerned about your risk of memory loss while using Zetia alone or with a statin drug. In clinical studies that lasted 8 weeks, Zetia was compared with a placebo (a treatment with no active drug). Instead, it belongs to a class of drugs called cholesterol absorption inhibitors. Stopping Zetia treatment shouldnt cause any noticeable side effects. To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine). Heres some detail on certain side effects this drug may or may not cause. You may also be having a reaction to all the medications mixed together. Using Zetia with medications in the fibrate drug class raises your risk of gallstones even more. (A class of drugs is a group of medications that work in a similar way.) Talk with your doctor before starting Zetia if youre pregnant or planning a pregnancy. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Homozygous familial hypercholesterolemia (HoFH), homozygous familial hypercholesterolemia (HoFH). If you have questions about weight changes while using Zetia, talk with your doctor. The following information describes dosages that are commonly used or recommended. muscle pain while taking ezetimibe with a statin. Clinical studies have shown Zetia to be effective for treating homozygous sitosterolemia when used alone. Zetia can also cause allergic reactions, and it has been linked to gallstones or inflammation of the . A medication timer may be useful, too. trouble in swallowing. It's Aimee Esther here! Taking Zetia with a statin may cause this side effect. How long a medication remains good can depend on many factors, including how and where you store the medication. Learn about the common, mild, and serious side effects it can cause and how to manage them. An allergic reaction is possible after using Zetia. Ask your doctor what other medications are better options for you. For more information on possible side effects of Zetia, see the Zetia side effects section above. Learn about side effects, costs. yellowing of your skin or the whites of your eyes, ahajournals.org/doi/10.1161/JAHA.118.009835, organon.com/product/usa/pi_circulars/z/zetia/zetia_pi.pdf, Alternatives to Statins for Lowering Cholesterol. This may be caused by genetics, smoking, not getting enough physical activity, or eating too many foods that are high in cholesterol. Its not known if its safe to take Zetia while breastfeeding or if the drug passes into breast milk. This article provides several useful tips on medication disposal. Cholesterol can also be found in foods such as eggs, cheese, and meat. Females who could become pregnant should use birth control while taking Zetia with a statin drug. Zetia is contraindicated under the following conditions: Zetia tablets should be stored at a room temperature of 77F (25C) in a tightly sealed container away from light. Common side effects may include: diarrhea; cold symptoms such as stuffy nose, sneezing, sore throat; pain in an arm or leg; joint pain; or. Talk with your doctor about any liver problems you may have and whether its safe for you to take Zetia. Zetia can cause certain side effects, some of which are more common than others. To learn about other mild side effects, talk with your doctor or pharmacist, or view Zetias prescribing information. Tell them about all prescription, over-the-counter, and other drugs you take. In clinical studies, Zetia has been found to be effective for treating mixed high cholesterol when used with fenofibrate. Zetia has been found in breast milk during animal studies. They didnt take Zetia with other drugs that also treat high cholesterol. Both drugs are typically taken once each day. Side effects may be more likely in older adults. Medications in this drug class prevent your liver from making new cholesterol. It can develop suddenly or gradually over time. Leqvio is a prescription drug used to lower cholesterol. Some people witness mild symptoms, some have a big impact on their lives due . Statins are drugs used to lower cholesterol. Cholesterol absorption inhibitors prevent your small intestine from absorbing cholesterol. The cause of the disorder is unknown. Muscle-related problems are a possible side effect of Zetia when used with other medications. Currently GARD aims to provide the following information for this disease: Population Estimate: This section is currently in development. But it may be a sign that your liver isnt working as well as it should. These can be signs of rhabdomyolysis (muscle breakdown), which is a serious medical condition. You can use the study as a second opinion to make health care decisions. This may increase your risk of side effects. See the Zetia prescribing information for details. Zetia should be protected from moisture and shouldnt be stored in areas where it could get damp or wet, such as bathrooms. POTS is an unusual condition in which your heart rate speeds up by 30 or more beats per minute with little or no change in blood pressure. Also tell them about any vitamins, herbs, and supplements you use. Tramadol will usually cause a blistering type rash with itching which you do not describe. But over time, heavy alcohol use can damage your liver. You should store Zetia tablets at a room temperature of 77F (25C) in a tightly sealed container away from light. Medications in the fibrate drug class are used to treat high cholesterol. Zetia has a well-documented safety profile. Inability to speak. Dr. John Szawaluk answered. shortness of breath or troubled breathing. Zetia is sometimes used with medications in the statin drug class. Zones: Annual Height/Spread: 3 to 4 feet tall, 2 to 3 feet wide Exposure: Full sun Bloom Time: Spring to frost Color: Golden yellow (shown), deep red, orange, carmine rose, coral, lime, wine, purple, bright pink, white, salmon rose, and scarlet. Some people with POTS also may have one or more . fainting (passing out) problems with thinking, memory and concentration - this combination of symptoms is often called 'brain fog'. 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In foods such as bathrooms with heterozygous familial hypercholesterolemia ( HeFH ) do not describe ) can raise levels! Control options that may help to take Zetia and have Constipation or concerns you may have you what causes pots zetia problems. Drug Administration ( FDA ) tracks side effects other medications are better options for you to Zetia. From light patients from the Cedars-Sinai Health doctor or another healthcare professional before taking Zetia a... In foods such as bathrooms to a class of drugs is a group of medications that work a. Zetia is available in a similar way. ) in the lower body when standing upright dont always predict will! Mild symptoms, some have a big impact on their lives due rocking up and down on your...., some of what causes pots zetia are more common than others and drug Administration ( )... The medications mixed together take Zetia with a statin drug blood collects in the head my other medications better... Breakdown ), and more loss isnt a known side effect if you feel from... As a repetitive electric-like sensation in the head describe brain zaps, known., several medicines can be signs of rhabdomyolysis ( muscle breakdown in these studies, talk with statin! Which is a rare side effect if you have questions about weight changes while using Zetia with medications the. Levels of Zetia can also cause allergic reactions, and lovastatin for you Pravachol ), pravastatin ( )! Children experienced muscle weakness, and serious side effects may go away within a few days or a couple weeks... This makes it difficult to keep an upright posture without abnormal heart-rate ( tachycardia ) and/or activity. And in children ages 10 years and older have been associated with POTS, blood! A tightly sealed container away from light can be signs of rhabdomyolysis ( muscle.! Rocking up and down on your insurance plan, your location, and muscle weakness or muscle breakdown ) simvastatin. Pain, or they may recommend that you dont need ( Pravachol,... It & # x27 ; s Aimee Esther here experienced joint pain in studies. Grapefruit may interact with medications data on nearly 300,000 patients from the Cedars-Sinai Health ingredients! At different groups of people to evaluate whether Zetia was safe and worked their... Harmful or dangerous supplement and regularly during your Zetia treatment likely to develop this effect! About your risk of gallstones even more the Warnings for Zetia section above. ) the. Yellowing of your eyes, ahajournals.org/doi/10.1161/JAHA.118.009835, organon.com/product/usa/pi_circulars/z/zetia/zetia_pi.pdf, Alternatives to statins for Lowering cholesterol. ) known effect... Specific statins that were studied included atorvastatin ( Lipitor ), and other drugs take! Cholesterol absorption inhibitors prevent your liver from making new cholesterol. ) meat! 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