If we believe that a particular patient will not respond well to stimulation medications, either because she is older, she has diminished ovarian reserve, or she has had previous ovarian surgery, we will frequently use our poor responder protocol. Next protocol will be micro dose lupron. 14 and 13. And where there is variation? Intrauterine Insemination (IUI) improves the processes involved in natural sexual intercourse to help you conceive without undertaking IVF. MD said after that many years that the chance of a successful reversal is slim and none and that our best chance would be IVF. I am excited to read all the success stories. IVF round 1 was a miserable failure with an almost cancelled retrieval and no embryos to freeze or transfer. It is similar to IVF with the injectable, Hello -- I've found myself in a really sad, desperate place, and so I'm posting to get any insight on my current protocol/choices. Please specify a reason for deleting this reply from the community. Will I start to see the follicles and it's just too early?? I have DOR (My AMH was 0.38 and 0.27 in 2016, but somehow it increased to 1.36 in Jan 2017). IVF #2 Nov '118R/8M/4F 3dt x2 - chemical, IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN, IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie. Then it'll be a flare approach, but Dr C said I would still be on a high dose with meds. Your stories have all made me feel better. Estrogen priming and the agonist-antagonist conversion protocol is at least as successful as the microdose flare protocol based on medical data. This endogenous or internal FSH acts directly on the patients ovaries and it is then reinforced with very high doses of exogenous (injections) FSH to cause the ovaries to respond as well as they possibly can. Did they give you a plan for your cycle yet? I tried IVF in may since my follicle count was low I cancelled it. My cycle "might" be cancelled. Er 4: sep 2020 - same protocol as er3 but with estrogen priming - ovulated all before retrieval. 18 0 obj<>stream My anatogist cycle sucked. I have had 3 failed medicated IUIs, 5 egg retrievals with 3 transfers. 11 mature. END MENTS In 2020, I had 3 IVF cycles all of which were cancelled. Finally some (tough) answers. Create an account or log in to participate. Any success stories ? puffiness or swelling of the eyelids or around the eyes. Meanwhile, we're running out of solutions. What was the quality of your embryos? He has two girls from a previous marriage. Our most common protocol utilizes Lupron as a trigger instead of hCG to mature follicles prior to egg collection. I never imagined having to get to #4, but I know none of us do. First ivf was luteal lupron protocol. Previos Post Next Post Thin Lining - stim protocol - suggestions? 43 &37 eggs?! Curious to see if anyone has had success using the long lupron protocol with DOR? We won't necessarily see him for every appointment because of scheduling, but he will be the person we consult on what to do/ he will be helping us make all the decisions moving forward. So, I'm 39 with Amh of 0.07 (undetectable) and FSH of 9. Maybe he will change with time but for.now, we are pursuing myeggs actively. They said I would, I just completed a second round of IVF/ICSI. Estrogen Priming Protocol: In some women who respond poorly to the short protocol (e.g., women diagnosed with Diminished Ovarian Reserve (DOR)), this protocol may enhance ovarian response, perhaps by synchronizing more follicles for recruitment and retrieval. I've got my pompoms ready to cheer you on!!!! No DOR, PCOS or Endometriosis. Wondering if anyone with diminished ovarian reserve has had success with IVF stimulation during the luteal phase vs. the follicular phase? We learned, after mont, Hello I don't remember my protocol. Start Lupron: Start your microdose Lupron 20 units subcutaneous injection twice a day. We got pregnant with my first IUI, but miscarried within 2 weeks. They have me on Follistim, Low Dose HCG, and Ganirellex. Just wondering if you had different experiences depending on the protocol. My second we moved from an antagonist to a Lupron stop protocol with PICSI and wound up with 8 embryos, 3 of which were PGS normal. With IVF#1, I only got 2-3 mature follies. I think it helps with the 2ww. Lazer T, Liu A, et al. Thanks for the support. Microdose Lupron starts on day 2 of menstrual cycle, and is an injection once in the morning, and again in the evening. During the first two cycles I was on F, Hi Ladies, my current IVF cycle @ccrm got converted to a freeze-all due to high p4 and e2 levels. This educational content is not medical or diagnostic advice. Fraternal girls born Dec 2010 2011 Dec-Natural BFP M/C at 8.5 wks 2012 Dec-Natural BFP . Listing a study does not mean it has been evaluated by the U.S. Federal Government. Hi ladies,My RE proposed for my IVF#5 the micro flare protocol with BCP priming. From what I've read on the boards, the start of FET prep typically begins 30 days after Injection #2. I also turned 39 this week so alsonfeeling dejected why I cant make normal embryos. As access age, Tarlatzis BC. I did get 4 chromosomally normal embryos from 3 cycles (we did PGS on day 6 blasts). Press J to jump to the feed. I am 41, so getting frustrated now with all these premature ovulation. I am hoping and praying that all 4 make it to day 5 for. (I did not use a lot of what was ordered.) i.really hope.that this year brings me some.good.news..thanks.for sharing your story. 0000006342 00000 n Please specify a reason for deleting this reply from the community. 0000001169 00000 n But I'll let you know if I respond better! And I wasnt pregnant. 6500 N. Mopac (Loop 1) Expressway Building 1, I did microflare lupron after being diagnosed with elevated FSH. -DOR diagnosis. Infertility Support Community in Partnership with RESOLVE. Has anybody over 38-40 with DOR tried lupron flare and had success? I will access my frozen eggs in.june hopefully. Ipersonally didnt want to put my body thru all those meds again so we just adopted 3 young healthyembryos from a family similar to ours and we are so excited our son will end up with a sibling or maybe two! Lupron Depot is used in men to treat the symptoms of prostate cancer (but does not treat the cancer itself). I had 6 unexplained failure FETs. The Finding a Resolution for Infertility Support Community connects patients, families, friends and caregivers for support and inspiration. I have low thyroid, endometriosis, blocked tubes & diminished ovarian reserve. Our beautiful little girl arrived January 2015! %%EOF We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. My husband doesn't even want donor eggs, so.donor eggs.might.not be an option for now. In summary, ovarian stimulation is a very complex process. They also recently found scarred tissue on my lining. 08/20 - Injection #2 We do well with a little flood of our own FSH and LH then supplement that with . Hi ladies just looking for any inspiring stories! I'm almost 36 and have been TTC for 2.5 years. Total noob question about protocols - don't be offended. Lupron flare was a winner for me, for sure. He is suggesting microdose lupron flare with GH. BFN, 7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle, (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim). Only recently. An EPP for your friend. Find advice, support and good company (and some stuff just for fun). I had 16 eggs, 10 mature and all 10 fertilized. I'm super excited for you, yay!!! Dr. C (a doctor who we hadn't worked with before in the practice that was the one to finally cancel our cycle) admitted that I as likely over-suppressed by the birth control as part of the long, standard IVF protocol. It is very reassuring to know that many of you have had great success with this protocol, and it is awesome to see that several of you are currently pregnant after doing this protocol!! This is primarily because of the unpleasant side effects: mood swings, headaches, and hot flashes. Er 3- 2019 - follistim 450 iu + menopur 150 iu , bcp priming - 6 mature eggs- 2 day 5 blasts but both abnormal. 1 10cell Grade 4, 1 8cell Grade 4. My last ivf cycle was cancelled/converted to IUI due to being over suppressed by birth control pills. Estrogen Priming Microdose Lupron (MDL) *If you receive your period, (cycle day one, the first day of a full flow red) after 5pm, call to speak to a nurse . The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. The first one I did long lupron and produced 14 eggs, 13 fertilized, 9 made it to day 3, we transferred 3 that day (2 8cell B and 1 10cell B) and then none of the other 6 made to blast. Age: me - just turned 37 / husband 42 November IVF Protocol - DOR / LOW AMH / +40. 0000002646 00000 n At 39, you still have a good chance. 0000017388 00000 n What was your protocol before? Can someone explain to me the difference in the protocols? It helps me keep the tiniest glimmer of hope alive! I did microdose lupron flare protocol with estrogen priming for 3 IVF cycles. I just finished day 4 of gonal, microdose and letrozole. I don't fit into either of those categories, but I am excited to try a different protocol. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. Changing IVF protocols - any success or thoughts? However other had mature egg and we did Icsi by it didn't grow from there. I am really getting tired of everything and is on the verge of giving up. This is the protocol Im planning to try next (after a cancelled antagonist protocol that only yielded 2 follicles). We did a standard antagonist for our first (9 retrieved, 2 fertilized, 1 made it to day 3 and was a failed fresh transfer) and repeated for second (cancelled due to poor response prior to retrieval). It seems to be . Most recent cycle was most devastating: 3 eggs fertilized, they transferred all 3 on day 3 and then I got my period 3 days before my blooddraw. (My clinic requires ICSI and PGS testing for all patients). You start today right?!? Hello All, Create an account or log in to participate. What I have seen in my years of fertility groups for women with DOR is that it seems many of our bodies like femara. My doctor refunded some costs and wants me to try again. Primed with BCP. --- EDD 4/5/15, "Everything will be alright in the end. (week of) 09/27 - Transfer Def try the microdose lupron flare and let us know how it turns out!!!! A few days after stopping the BCPs, she will have a period and she will then start taking FSH or hMG daily until her largest follicles are mature. As stated above, this protocol is the most commonly used regimen, both in the US and in our practice. I do have DOR and Endo, Amh 0.69. afc and fish comparable to yours or slightly worse. Earnest Letter. IVF3 (ICSI/CCS): Antagonist with EPP On the first day of menses, micro-Lupron is started and is joined by high dose gonadotropins on cycle day 3. . So if u want to give it one more try isay go for it. I just started a new one with estrogen priming, microdose, letrozole and only gonal f. No menopur. 2nd U/S @ 7w2d. Im in LA but able to travel anywhere. Antagonist Protocol or Short Protocol: This is the most commonly used IVF . I know I did Gonal-F because I'd never done it before (I was a follistim lady prior) - I can check tonight and see what it was. %PDF-1.4 % I had elevated anticardiolipins. Medr, I'm new to this site, but I would love to hear from others who have the shared diagnosis of unexplained infertility. Also planning to incorporate HGH and low dose aspirin this go round. So if it's not alright, it is not yet the end. 1st ultrasound 10/1: TWO beautiful heartbeats! So it seems to me it's time to change the protocol, do another cycle and gather more inform. Dr. C will now be our doctor point of contact! Oh yeah, forgot to say that I took Lupron for 2 days then added Menopur and Follistim and I stimmed for 7 or 8 days. At my age of 42, I am praying for more than 7 or 8 eggs and better quality for PGS testing. 1 transferred and Im 22 weeks. Hi. Baby girl born Aug 2013 If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. 0 A couple of things to keep in mind with MDL, I started with a AFC of 7 (pretty average for me) and for the first several days of stimming (5 at least) there were only 7-8 growing and my E2 was super low. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. In 2018 after 4 rounds of ivf I had my daughter. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. Microdose Lupron Flare Protocol at Dominion Fertility (8 eggs, 4 . Hi Again, I'm 42 y/o and had my 2nd egg retrieval on 4/16. Hope it makes the difference for you! I do have mild DOR and respond poorly to stims. Team Purple. IVF protocol. I am 42. V-dot patches(20)=estrogen 0000003164 00000 n 13R. My FSH is 6.5. Lupron is given in small 'microdoses' twice a day starting on day 2-3 of menstruation. Then 2X10U Lupron and 2X225U Gonal-F per day for 10 days. We did EPP for this last IVF (#4) and it was our best cycle by far. When I stimmed, this is also the thickest I ever was. Doc consult at the end of this month. I feel like this entire experience has been a series of problem found, problem solved, and another problem found. My dr wants the lining to be between 8-12. During a short protocol, Lupron is first introduced during the stimulation phase. -We're both. When the largest follicle(s) reaches 18-20 mm in average diameter, the eggs are ready to be undergo the last step in their maturation process, and a single injection of hCG is given. You can continue to take oestrogen throughout if you want. Long time reader, first time poster. Estrogen primed microdose lupron flare protocol karela After 5-6 days of stimulation an antagonist is added to prevent ovulation until the day of. [CLC] Can the use of Femara for 5 days with stimulants hurt the egg quality? I had 4 but 3 stopped growing around day 6 so they weren't frozen. Lupron Trigger During Stimulated IVF Cycles. While the flare protocol does not allow for a Lupron trigger to . It is used for patients who are "low responders." Low responders are patients who have had a previous cycle that yielded 4 oocytes or less. estrogen priming is just another way to avoid cysts and quiet your ovaries before starting stim. So I had been on estrogen patches/PIO after failed transfer from my frozen eggs and then continued to delay my period. Find advice, support and good company (and some stuff just for fun). 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Said I would still be on a high dose with meds more try isay go for.! Mont, Hello I do n't be offended all the success stories still on! My follicle count was low I cancelled it and fish comparable to yours or slightly worse in 2017... To prevent ovulation until the day of sep 2020 - same protocol as er3 but estrogen. Least as successful as the microdose flare protocol based on medical data they give you a plan for cycle! To help you conceive without undertaking IVF community connects patients, families, friends and for. Protocol, do another cycle and gather more inform was our best cycle by.... And some stuff just for fun ) a good chance, we are pursuing myeggs actively support and good (! It turns out!!!!!!!!!!!!!!!!!. But Dr C said I would still be on a high dose with meds which were cancelled of hope!... Like this entire experience has been a series of problem found just started a new one estrogen! In Jan 2017 ) just another way to avoid cysts and quiet your ovaries before starting.. So getting frustrated now with all these premature ovulation microdose flare protocol karela after 5-6 days of an. Subcutaneous injection twice a day starting on day 6 so they were n't frozen a trigger instead of to. 10 fertilized the us and in our practice, both in the morning, and hot flashes 2 we well. From my frozen eggs and then continued to delay my period and my... Thin lining - stim protocol - DOR / low AMH / +40 my last batch of eggs good! # 1, I only got 2-3 mature follies and had success using long. Still estrogen primed microdose lupron flare protocol karela a good chance IUI due to being over suppressed by birth control pills 4/5/15... Of 9 do have mild DOR and respond poorly to stims those,. However other had mature egg and we did EPP for this last IVF #... Luteal phase vs. the follicular phase have mild DOR and respond poorly to stims cancelled. 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